First in-human results
In 2011 our research group performed the first in-human fluorescence study concerning intraoperative staining of ovarian cancer.
Read moreVisualization of tissue with molecular imaging
In 2011 our research group performed the first in-human fluorescence study concerning intraoperative staining of ovarian cancer.
Read moreThe TRACT-I was the first study that utilized NIR spectroscopy in rectal cancer patients using Bevacizumab-IRDye800CW.
Read moreIn 2014 the first study started using systemic and topical administration of a fluorescence-labelled antibody against vascular endothelial growth factor (VEGF) utilizing a NIR infrared camera system.
Read moreStart of ICON study; the first Head and Neck Cancer study at OMIG. The ICON study is a clinical trial for the intraoperative assessment of tumor margins during surgical treatment using cetuximab-IRDye800CW
Read moreThe Thyroid Cancer Target study is a dual study. The first part started in 2018, using EMI-137 in targeting thyroid cancer. The second part started in 2021, utilizing Bevacizumab-IRDye800CW.
Read moreThe VISION study is the first study that focussed on IBD pathology. In this study Vedolizumab-800CW is utilized to identify inflamed gut mucosa using near-infrared fluorescence molecular endoscopy (NIR-FME), spectroscopy and confocal laser endomicroscopy (CLE).
Read moreAdhering to the new MDR regulations we have constructed our own fluorescence endoscopy system and started using the system in our clinical studies.
Our first clinical study in which we can base clinical decisions on fluorescence imaging.
Read moreKeizers B, Nijboer TS, van der Fels CAM, van den Heuvel MC, van Dam GM, Kruijff S, Jan de Jong I, Witjes MJH, Voskuil FJ, Gorpas D, Browne WR, van der Zaag PJ. Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW. J Biomed Opt. 2025 Jan;30(Suppl 1):S13708. doi: 10.1117/1.JBO.30.S1.S13708. Epub 2024 Nov 15. PMID: 39553388; PMCID: PMC11566260.
- Read moreMetman, M.J.H., Jonker, P.K.C., Sondorp, L.H.J. et al. MET-receptor targeted fluorescent imaging and spectroscopy to detect multifocal papillary thyroid cancer. Eur J Nucl Med Mol Imaging (2023). https://doi.org/10.1007/s00259-023-06525-5
- Read morede Wit, J.G., Vonk, J., Voskuil, F.J. et al. EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial. Nat Commun 14, 4952 (2023). https://doi.org/10.1038/s41467-023-40324-8
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